I play 4..Nd4. kinda expect to win as black. Support the d4 square and all is good.
unless white wants to get black out of preparation early, i do not find any good reason for doing c2-c4 against sicilian (ok in case of later d2-d4 we go in some standard positions), it is like loosing of tempo but for nothing since black still can go with d7-d5.whenever i tried this approach i was not happy at all with my positions.
Even in lines with later d2-d4 (which is mandatoy otherwise with d7-d5 black will go better considering weak d4 and d3 squares) this pawn may be target at c file...white bishoop is enclosed...
I have played these lines in casual games with @Bad_Dobby_Fischer and done some analysis. What do you think? c4 is relatively rare but the real point of discussion I think is the idea of Be2 and castles and the d4 break later when black no longer has the strong and thematic cxd4 and Bb4