The open sicilian is good. I play it and enjoy it.
1. e4 c5 2. Nf3 (any reasonable Black move except a6) 3. d4
That line isn't nearly so good against 2. ... a6, though.
If you prefer a quieter game, the closed sicilian is also good.
1. e4 c5 2. Nc3 followed by g3 and Bg2.
I was wondering what is a good system against the Sicilian defence?