There are many variations to each opening, leading to all sorts of play, so it's hard to write a few sentences that sum up the two openings. Also I want to add that the semi slav is a 3rd, completely separate opening.
But ok, you're just asking about QGD and slav.
In the most basic terms, I guess I'd say in the slav you're giving up the center with an early dxc, and in the queen's gambit you're holding on to d5.
In the QGD and semi slav you're usually needing to play c5 or e5 at some point in the first 15 moves, but in the slav it's more about piece play.
When I was new I thought the biggest difference was the light square bishop too... but for example in the tartakower QGD the light square bishop is perfectly happy and active on b7. So it's not really about that.
In general the QGD will lead to positions that are easier to understand than the slav and semi slav... that's not to say only beginners play it, tons of GMs and world champions play it too. So don't pick the slav or semi slav because you think that's what good players do, pick the opening that leads to middlegames you like. That's the whole point of the opening.
I'm trying to find a good defence to 1 d4. I've tried King's Indian but find it to fiddly.
The Orthodox locks in the Queens bishop while the Slav doesn't . Yet the orthodox seems to be more popular. What is it's advantage?