For what purpose? Is this for your over the board tournament prep-work? Are you writing an opening manual?
which chess opening database to follow ?

These databases show different numbers because each one collect games on their own. Top level games (such as the GCT, WC, the Candidates and all FIDE rated GM/IM events) are included in any database. Some lower level tournaments however, especially locally organized ones, may not be included in a database because they cannot access the games, or because it’s determined that the games are of low quality.

@inkspirit it's confusing if i take one as a base, for instance, let's say i chose a move of a preferred line depending on the winning percentage of this move as white player, in that case i am wrong bcoz my base database site is a alien site showing me not up to date data because i see different data in milky way galaxy planet websites.

"Without opening moves/games database you can't do analysis, exploring of opening moves, it's a must required tool."
What do you think people did before game databases?

@inkspirit it's confusing if i take one as a base, for instance, let's say i chose a move of a preferred line depending on the winning percentage of this move as white player, in that case i am wrong bcoz my base database site is a alien site showing me not up to date data because i see different data in milky way galaxy planet websites.
If you're basing your moves on winning percentage? You're going about this wrong. Lets say, you play a certain opening. And move 8 has a winning percentage of 61%. But it hasn't been played in 2 years. You need to know why that move isnt played anymore.
You must remember this …

Follow Chessbase Openings database. It's the publisher of Fritz GUI, Fritz Power Book, Megadatabase, etc.

The problem with following database lines is that we reach positions and dont understand how we got there. The line may be good and solid and all, but sooner or later someone is going to usually deviate and we are on our own. Best to play what we understand I think.

A good chunk of some of those databases are Blitz games and Bullet games. That may explain some of the discrepancies. Other factors are the ratings of the players in those databases, and normal statistical variance.
If you are searching for the "truth" of the positions, best to limit your results to Master-level classical games. If you are searching for traps or practical effectiveness, include those lower level games with quick time controls.
I would consult all three databases if you have access.
Against 1.e4, black's first move 1..c5 shows 424206 games for chess.com and 449389, 392231 games on other database explorers.
Without opening moves/games database you can't do analysis, exploring of opening moves, it's a must required tool.
So, how we can do these things if different database websites show different numbers? which database explorer should be trusted? it's confusing because if we take one website database as a base for exploring opening moves for different purposes then who can guarantee that this site's data is right than others which show different data, so our exploration may be wrong.
Which chess opening database to follow when they showing different numbers of games and black/white winning percentages ??!
Thanks for your time, no wasting comments plz, it's a serious topic regarding the usage of opening/games database.
Any IM or GM will tell you. It's not chess.com's, though it's respectable. By far, the one EVERY Super-GM uses, is chessbase.
Against 1.e4, black's first move 1..c5 shows 424206 games for chess.com and 449389, 392231 games on other database explorers.
Without opening moves/games database you can't do analysis, exploring of opening moves, it's a must required tool.
So, how we can do these things if different database websites show different numbers? which database explorer should be trusted? it's confusing because if we take one website database as a base for exploring opening moves for different purposes then who can guarantee that this site's data is right than others which show different data, so our exploration may be wrong.
Which chess opening database to follow when they showing different numbers of games and black/white winning percentages ??!
Thanks for your time, no wasting comments plz, it's a serious topic regarding the usage of opening/games database.