The Sicilian is an opening which arises from 1. e4 c5. If White plays a different opening move then you'll also play a different opening.
Some openings overlap though. For example, the Modern Defense is where Black plays g6 on their first move, but it has the same name against both e4 and d4.
If you are familiar to using an opening which you can use in most games as Black then I would suggest looking up some information about and preparing to play the King's Indian Defence. It's a solid setup that you can play almost any time. It's also a modern opening so you'll likely catch out a few beginners who have been taught the main opening stuff of e4 e5, d4 d5 and other openings which follow the principle of 'control the center by occupying it'. Downside is you'll allow your opponent to control the game and steer the direction.
Hello, just a question from somebody trying to switch from Go and Shogi to Chess.
Being a player who plays black, can i use the Sicilian regardless of white's opening? I mean, can i always use the Sicilian?
This is a common practice in Shogi where players typically use an opening which they master and use in most of their games regardless of what the opponent is doing...
Thnx in advance!