STats show that 1.c3 is the best opening. Is crafty and mystery
do you like e4 d4 or c4

It depends on the database you're using. In most of them, 1. c3 scores <50% for White.
1. Nf3 ftw, not because I like exotic openings, but because it allows to transpose into openings that are more favourable for White, like the Maroczy Bind Sicilian or the Catalan (or the King's Indian Attack for those who prefer it), and sidestep unpleasant openings like the Petrov Defense and the Indians.
The second best option imo is 1. d4.

I like c4 as English is about flexibility, but I like to change to some Indian if they play e6 instead of e5

I play 1. e4, 1. d4, and 1. c4 all the time. They are my 3 favorite starting moves. I play those moves and I rely on openings and I am not a "Patzer". I am a regular player looking to improve. 1. e4 is my main opening line though.
witch one do you like beter