In the eyes of most people, losing a queen pretty much means you've lost. Unless, of course, the opponent is very low-rated. Continuing an already lost game usually isn't very appealing. So, many players prefer to resign and start another game instead.
loss of queen...

OP makes a valid point though. Especially in blitz. There's simply nothing to be lost by continuing to play on 100% after you lose the queen. If you lost it, he might lose it. If he doesn't, you just played 15-30 moves without your queen against a tough opponent. Either way, you're winning in the long run.
Weaker players also loosen up instead of tighten up when they go up a queen. Sometimes it's really easy to find tactical combos that net you 3 minors for the queen in the end or a rook and a minor. All of a sudden, the queen's win isn't so clear.
I'm often puzzled why people resign after losing the queen. I accept the queen is the most flexible of pieces and the task at winning is more difficult but but not impossible. I've had several opponents resign immediately after losing the queen, sometimes early in the contest, and it makes no sense to me.
I Lost Queens Too But Won
I So Agree With You Millenniumbug
Two Rooks For Queen Is OK.
Nice Forum.
Example Of Loss Of Queen:

I'm often puzzled why people resign after losing the queen. I accept the queen is the most flexible of pieces and the task at winning is more difficult but but not impossible. I've had several opponents resign immediately after losing the queen, sometimes early in the contest, and it makes no sense to me.
I Lost Queens Too But Won
I So Agree With You Millenniumbug
Two Rooks For Queen Is OK.
Nice Forum.
Example Of Loss Of Queen:

Losing the queen isnt the end of the game as you still have rooks and as long as they capture pieces and survive the player will be ok.

Losing the queen isnt the end of the game as you still have rooks and as long as they capture pieces and survive the player will be ok.
I'm often puzzled why people resign after losing the queen. I accept the queen is the most flexible of pieces and the task at winning is more difficult but but not impossible. I've had several opponents resign immediately after losing the queen, sometimes early in the contest, and it makes no sense to me.
I Lost Queens Too But Won
I So Agree With You Millenniumbug
Two Rooks For Queen Is OK.
Nice Forum.
Example Of Loss Of Queen:
You had enough compensation for the queen. We are talking about people resigning when they are down a queen with little or no compensation.
When Queen Down, People Resign But Why Muhmmad Areez10?

I'm often puzzled why people resign after losing the queen. I accept the queen is the most flexible of pieces and the task at winning is more difficult but but not impossible. I've had several opponents resign immediately after losing the queen, sometimes early in the contest, and it makes no sense to me.
Some times, when promoting a pawn,
there are other, and better, altenatives
- than a Queen ...
If you still have some threats in the position, play on.
If no threats, don't waste your time.
Do you think my opponent was mad after this game?
I'm often puzzled why people resign after losing the queen. I accept the queen is the most flexible of pieces and the task at winning is more difficult but but not impossible. I've had several opponents resign immediately after losing the queen, sometimes early in the contest, and it makes no sense to me.