Vacation is limited and your opponents will eventually come of vacation and move, run out of vacation an move, or run out of vacation and lose on time.
The site will deal with people dragging out games in completely hopeless positions if they are using vacation to drag out games but that is really the only thing that will impact things.
https://support.chess.com/customer/en/portal/articles/1444860-what-is-vacation-abuse-
Buongiorno, gioco molte partite giornaliere, ed al momento ho almeno un paio di giocatori che si sono messi in vacanza per evitare la sconfitta, e sono in vacanza da settimane.