Medics: what is the answer to this question?

But there can be doctors who care about the theory of evolution on a forum 

There’s no harm in giving a shot, we have doctors also in forums, someone will likely be able to answer based on years of experience  and it will be nice to have medical discussions also

Thanks, that’s a contraindication since you said it’s reduces the efficacy of Rifampicin   Hmm and if that be an indication concerning women which i don’t think is... why so ? Will it be transmitted to the baby? I thought tb is gotten through inhalation of the droplets or skin penetration or ingestion only.

Contraindications means when it shouldn’t be used or disadvantages. Indications means uses 

Okay. Tuberculosis is an infection caused by a bacteria called Mycobacterium tuberculosis mainly.
The drugs for the treatment of tuberculosis;
A) we have the FIRST line drugs which are:
1. Rifampicin
2. Pyrazinamide
3. Isoniazid
4. Ethambutol
5. Streptomycin

B)The SECOND line drugs or reserve drugs which are:
1. Ethionamide/prothionamide
2. Ofloxacin/levofloxacin/moxifloxacin
3. Cycloserine/terizidone
4.Kanamycin/amikacin
5.Capreomycin
6.Para-amino salicylic acid

C) and in some cases corticosteroids are used like prednisone ( anti-inflammatory

MECHANISM OF ACTION these drugs simply is to inhibit the production of mycolic acid which is a component of the bacteria that causes Tb. Mycolic acid prevents our white blood cells from fighting it and destroys the power house of our body cells ( mitochondria) . It also helps the bacteria to let’s say grow or multiply.
.....................
COCPS are combined oral contraceptive pills it is a combination of progestin and estrogen.

The two commonly used estrogens are ethinyl estradiol and mestranol which If you use cocps you will see.

While Progestins commonly used are levonorgesterel, norgestrel, norethindrone , norethindrone acetate and ethinodiol.

MECHANISM OF AACTION OF COCPS: So basically the way Cocps work is to inhibit ovulation by acting on certain hormones in the pituitary gland and also modifying the cervical mucus to make it difficult for sperm to travel simply

So, roommate asked me this question that a consultant  asked when Combined oral contraceptives are used in the treatment of tuberculosis ( indication ) and without giving an answer left it for research . She couldn’t find the answer after searching the internet, she asked me and I was speechless  and I’m also curious as I don’t see the correlation. Hence, I decided to turn this into a topic.   As you can see even from the mode of action as I highlighted above of these two drugs; one is for killing a bacteria and the latter for preventing conception. How do they work together ?

But can tuberculosis be spread from mother to foetus ? Has it ever been reported or happened ?

Ok so you are saying cocps are given to protect the transmission of tb from mother to child by preventing conception, thanks doc 😉👍🏼

I was about to say this, thanks for saving me the stress